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Neurological disturbances in a rare primary osteoarthropathy
Francesco Paolo Cantatore, Carmine Alessandro Acquista, Vincenzo Pipitone
Dipartimento di
Medicina Interna e del Lavoro, Sezione di Reumatologia, Università
degli Studi di Bari, Bari, Italy
Correspondence to: Dr FP Cantatore, Via dell'Andro 21, 70037 Ruvo (Bari), Italy
Accepted 22 June
1998
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Introduction |
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A 40-year-old man and a 29-year-old woman with clubbed fingers and toes and other foot and knee deformities presented with symptoms of pain and paraesthesia in the forearms and hands which were more intense during the night, for 5 and 2 years, respectively. Skeletal X-ray showed general soft-tissue swelling with digital clubbing, irregular periosteal proliferation with cortical thickening of the radii, ulnae, metacarpal and metatarsal bones, phalanges, femur, tibiae and fibulae. Mega-epiphysis of radii, femur and tibiae were also noted (figure). There was no evidence of pulmonary and cardiovascular diseases.
Ultrasound examination excluded, in both cases, the presence of flexor tenosynovitis or arthritis of the wrist. A series of investigations was carried out in order to exclude coexisting diseases such as diabetes, gout or pseudogout, connective tissue diseases, and hyper- or hypothyroidism. Other conditions, such as pregnancy, or mechanical causes were also excluded.
In both cases clinical assessment showed positive Tinel's sign
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