CASE REPORTS
Drug interaction with anti-mycobacterial treatment as a cause of clopidogrel resistance
Department of Cardiology, Morriston Hospital, Swansea, Wales, UK
Correspondence to:
Dr M Srinivasan, Department of Cardiology, Morriston Hospital, Swansea SA 6 6NL, Wales, UK; smanivannan70{at}hotmail.com
The case is reported of a patient presenting with recurrent acute myocardial infarction due to stent thrombosis resulting from possible clopidogrel resistance caused by interaction between clopidogrel and anti-tuberculosis drugs. A brief overview of drug interaction as a risk factor for clopidogrel resistance is given.
Keywords: anti-mycobacterial therapy; clopidogrel resistance; cytochrome 450 3a; dual anti-platelet therapy; stent thrombosis
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Interventional cardiology
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Drugs: cardiovascular system
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