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Postgraduate Medical Journal 2007;83:e4; doi:10.1136/pgmj.2007.062307
Copyright © 2007 The Fellowship of Postgraduate Medicine.

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Case report

One-year-old male with accelerated growth and development

Ajit Singh Kashyap1, Kuldip Parkash Anand2, Surekha Kashyap3 and Sumeet Arora4

1 Department of Endocrinology, Command Hospital (Central Command), Lucknow Cantt, India
2 Command Hospital (Eastern Command), Kolkata, India
3 Command Headquarters (Central Command), Medical Branch, Lucknow, India
4 Department of Radiology, Command Hospital (Central Command), Lucknow, India

Correspondence to:
Dr Ajit Singh Kashyap, Department of Endocrinology, Command Hospital (Central Command), Lucknow Cantt 226 002, India; kashyapajits{at}gmail.com

A 1-year-old male child with isosexual central (gonadotropin-dependent) precocious puberty caused by hypothalamic hamartoma is reported. Details of the diagnosis based solely on neuromaging characteristics, and satisfactory results of medical treatment with gonadotropin releasing hormone agonist analogues, are highlighted.

Abbreviations: CNS, central nervous system; FLAIR, fluid attenuated inversion recovery; GDPP, gonadotropin dependent precocious puberty; GnRH, gonadotropin releasing hormone; LH, luteinising hormone; LHRH, luteinising hormone releasing hormone; MRI, magnetic resonance imaging

Keywords: hypothalamic hamartoma; precocious puberty


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