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Postgraduate Medical Journal 2004;80:394-398; doi:10.1136/pgmj.2003.017095
© 2004 BMJ Publishing Group Ltd and The Fellowship of Postgraduate Medicine.
Postgraduate Medical Journal 2004;80:394-398
© 2004 Fellowship of Postgraduate Medicine

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Subclinical hyperthyroidism: to treat or not to treat?

E H Hoogendoorn1, M den Heijer1, A P J van Dijk2, A R Hermus1

1 Department of Endocrinology, University Medical Center Nijmegen, Netherlands
2 Department of Cardiology, University Medical Center Nijmegen, Netherlands

Correspondence to:
Correspondence to:
Dr E H Hoogendoorn
Department of Endocrinology, University Medical Center Nijmegen, PO Box 9101, 6500 HB Nijmegen, The Netherlands; e.hoogendoorn{at}endo.umcn.nl

Subclinical hyperthyroidism may be defined as the presence of free thyroxine and tri-iodothyronine levels within the reference range and a reduced serum thyroid stimulating hormone (TSH) level. In this review the prevalence of low TSH in the population and health consequences of subclinical hyperthyroidism, for example, effects on heart and bone mass, are discussed. Guidelines for treatment are given, based on expert opinion.

Abbreviations: BMD, bone mineral density; TSH, thyroid stimulating hormone

Keywords: cardiac effects; osteoporosis; hyperthyroidism; subclinical hyperthyroidism


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