© 2004 Fellowship of Postgraduate Medicine
CASE REPORT
Pneumocystis carinii pneumonia in chronic lymphocytic leukaemia
1 Department of Medicine, University Hospital of Zurich, Switzerland
2 Department of Pathology, University Hospital of Zurich, Switzerland
Correspondence to:
Correspondence to:
Dr Andreas Himmelmann
Department of Medicine, University Hospital of Zurich, Raemistrasse 100, CH-8091 Zurich, Switzerland; andreas.himmelmann{at}dim.usz.ch
Pneumocystis carinii pneumonia in patients with chronic lymphocytic leukaemia (CLL) who have not been treated with fludarabin are rare, although clinically relevant CD4 T-cell depletion can occur in longstanding CLL without prior treatment with purine analogues. A 52 year old woman is reported who was on long term treatment with chlorambucil and taking a short course of prednisone for familial CLL before she developped progressive dyspnoea, and P carinii pneumonia was diagnosed in bronchoalveolar lavage fluid. Despite treatment with high dose co-trimoxazole the patient died.
Keywords: Pneumocystic carinii pneumonia; chronic lymphocytic leukaemia
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