CASE REPORT

D-lactic acidosis secondary to short bowel syndrome

D L Zhang, Z W Jiang, J Jiang, B Cao, J S Li

Research Institute of General Surgery, School of Medicine, Nanjing University, Nanjing, Peoples Republic of China

Correspondence to:
Correspondence to:
Dr Zhang Dianliang, Research Institute of General Surgery, Jinling Hospital, 305 East Zhongshan Road, Nanjing 210002, Peoples Republic of China;
phdzdl{at}yahoo.com

A 12 year old boy presented with 11 episodes of weakness, ataxia, nausea, slurred speech, dehydration, and sometimes severe lethargy bordering on coma. A year previously the boy had small intestinal resections leaving 20 cm of small bowel remaining. D-lactic acidosis was diagnosed on the basis of a D-lactate level of 5.23 mmol/l. The clinical presentation of the disease is recurrent episodes of unusual neurological manifestations and severe metabolic acidosis. The diagnosis is dependent on the presentations and the plasma D-lactate level. Development of the syndrome seems to be the effect of the accumulation of D-lactic acid.

Keywords: D-lactate; D-lactic acidosis; short bowel syndrome

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