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Postgraduate Medical Journal 2002;78:366-367; doi:10.1136/pmj.78.920.366
Copyright © 2002 The Fellowship of Postgraduate Medicine.
Postgraduate Medical Journal 2002;78:366-367
© 2002 The Fellowship of Postgraduate Medicine

CASE REPORT

Yoghurt biotherapy: contraindicated in immunosuppressed patients?

G MacGregor1, A J Smith2, B Thakker2 and J Kinsella3

1 Department of Respiratory Medicine, Western General Hospital, Edinburgh, UK
2 Department of Medical Microbiology, Glasgow Royal Infirmary, Glasgow, UK
3 University Department of Anaesthetics, Glasgow Royal Infirmary, Glasgow, UK

Correspondence to:
Correspondence to:
Dr Gordon MacGregor, Room D38, 2nd Floor OPD, Western General Hospital, Crewe Road South, Edinburgh EH4 2XU, UK

ABSTRACT

AUTHOR:e-mail address please A fatal case of Lactobacillus rhamnosus septicaemia after prolonged oral vancomycin for recalcitrant Clostridium difficile infection is reported. The patient was immunosuppressed with cyclophosphamide and steroids for Sjögren's syndrome. The administration of Lactobacillus spp as "biotherapy" may be hazardous in such circumstances.

Keywords: biotherapy; Lactobacillus rhamnosus; Clostridium difficile; vancomycin; Sjögren's syndrome


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