Adenocarcinoma of the lung in Chinese patients: a revisit and some perspectives from the literature
B Lama, W K Lama, C L Lama, G C Ooib, J C M Hoa, M P Wongc, K W Tsanga
a University of Hong
Kong, Queen Mary Hospital, Hong Kong SAR: University Department of
Medicine, b University Department of
Diagnostic Radiology, c University
Department of Pathology
Correspondence to: Dr Kenneth W Tsang, University Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong SAR, China kwttsang{at}hku.hk
Submitted 23 January
2001;
Accepted 17 May 2001
AIM
To establish an updated
clinical profile of adenocarcinoma of the lung.
DESIGN
Retrospective review of
clinical charts, chest radiography, and computed tomography of
consecutive patients who attended Queen Mary Hospital in Hong Kong
between June 1995 and December 1997.
RESULTS
In the 115 patients
studied, 13% were <40 years of age (33.3% ever smokers). Haemoptysis
is more common among patients with early disease, while finger clubbing
was detected more commonly among smokers and ex-smokers. Most (98.3%)
patients had abnormal chest radiology including presence of mass
lesion, pleural effusion, collapse/consolidation, and effusion.
Patients with adenocarcinoma were significantly more likely to be
younger, female, in advanced disease (stage IIIB and IV), non-smoker,
and symptomatic on presentation (p<0.05) than those with squamous cell
lung cancer (n=128).
CONCLUSION
The clinical profile of
Chinese adenocarcinoma patients should help clinicians in the diagnosis
and management of these patients.
Keywords: lung cancer; adenocarcinoma; clinical profiles
© 2001 by The Fellowship of Postgraduate Medicine
This article has been cited by other articles:
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Chan, E. C., Lam, S. Y., Tsang, K. W., Lam, B., Ho, J. C. M., Fu, K. H., Lam, W. K., Kwong, Y. L.
(2002). Aberrant Promoter Methylation in Chinese Patients with Non-Small Cell Lung Cancer: Patterns in Primary Tumors and Potential Diagnostic Application in Bronchoalevolar Lavage. Clin. Cancer Res.
8: 3741-3746
[Abstract] [Full Text]
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