Review
Amyloidosis
M F Khan, R H Falk
Amyloidosis
Treatment and Research Center, Boston University School of Medicine,
715 Albany Street, Boston, MA 02118, USA
Correspondence to: Dr Falk
Submitted 10 October
2000;
Accepted 9 March 2001
Amyloidosis is not a single disease but a series of diseases in
which there is extracellular deposition of a protein which, although it
may be derived from different and unrelated sources, folds into a 
pleated sheet.
There have recently been significant advances in elucidating the
pathogenesis and in the treatment of this group of disorders. By
identifying the source of precursor protein, treatment is aimed at
eliminating or reducing the extent of deposition and is tailored for
each patient.
Early diagnosis is required for the optimal effect of treatment on
patient survival and quality of life. An increased awareness among
physicians of the spectrum of the disease and tools to aid its
diagnosis is of increasing importance.
Keywords: amyloidosis
© 2001 by The Fellowship of Postgraduate Medicine
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