Case reports
Human immunoglobulin for diabetic amyotrophy
a promising
prospect?
A E Courtney, G V McDonnell, V H Patterson
Department of
Neurology, Royal Victoria Hospital, Grosvenor Road, Belfast BT12
6BA, UK
Correspondence to: Dr Courtney aecourtney{at}doctors.org.uk
Submitted 21 June 2000;
Accepted 2 October 2000
Diabetic neuropathies are universally recognised and cause
significant morbidity. At present improving glycaemic control is the
only recognised treatment. A man with type 2 diabetes presented with
disabling asymmetric lower limb proximal neuropathy. Rapid clinical,
functional, and electrical improvement followed treatment with
intravenous immunoglobulin. The aetiology of diabetic amyotrophy remains controversial but there is evidence for an immune mediated process and this case suggests a role for immunoglobulin in the management of this debilitating condition.
Keywords: diabetes mellitus; neuropathy; immunoglobulin
© 2001 by The Fellowship of Postgraduate Medicine
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