Adverse drug reaction of the month
Indomethacin induced psychosis
D Tharumaratnam, S Bashford, S A Khan
Department of
Elderly Care, Lister Hospital, Corey's Mill Lane, Stevenage, Herts
SG1 4AB, UK
Correspondence to: Dr S A Khan (shadidak{at}aol.com)
Submitted 20 July 1999;
Accepted 19 April 2000
Indomethacin is a commonly prescribed non-steroidal
anti-inflammatory drug. While its adverse effects on gastrointestinal and renal systems are well described, its central nervous system effects are less well known. This case report describes an elderly man,
prescribed indomethacin for gout, who presented with psychosis.
Keywords: indomethacin; psychosis; geriatric medicine
© 2000 by The Fellowship of Postgraduate Medicine
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