Causes of anorexia in untreated hyperthyroidism: a prospective study
Wei-Xin Dai, Xun-Wu Meng
Department of
Endocrinology, Chinese Academy of Medical Sciences (CAMS), Peking Union
Medical College (PUMC), and PUMC Hospital, Beijing, P R China
Correspondence to: Dr Wei-Xin Dai, Department of Endocrinology, Peking Union Medical College Hospital, CAMS and PUMC, Wangfujing, Beijing 100730, P R China (e-mail: daiwx{at}csc.pumch.ac.cn)
Submitted 22 June 1999;
Accepted 27 September 1999
Seventeen consecutive patients (mean (SD) 46 (11) years) with
untreated hyperthyroidism and anorexia and 29 patients (35 (9) years)
with untreated hyperthyroidism without anorexia were studied. The study
was conducted at the thyroid clinic of the PUMC Hospital, Beijing,
China from March to August 1997. The patients' ages, serum free
calcium, liver function and emotional state, specifically the level of
anxiety (using the self anxiety scale, Chinese version), were compared
before and/or after antithyroid drug treatment in the two groups. This
prospective study suggested that the causes of anorexia in untreated
hyperthyroidism are complicated. Older age, abnormal liver function,
and the level of anxiety are significantly related to anorexia in
untreated hyperthyroidism, but hypercalcaemia was not confirmed to be
related to anorexia in the study.
Keywords: hypercalcaemia; hyperthyroidism; anorexia; anxiety
© 2000 by The Fellowship of Postgraduate Medicine
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