Short report
Addison's disease in type 1 diabetes
presenting with recurrent hypoglycaemia
Vincent McAulay, Brian M Frier
Department
of Diabetes, Royal Infirmary, Lauriston Place, Edinburgh EH3 9YW
Correspondence to: Dr Frier
Submitted 1 June
1999;
Accepted 6 September 1999
Primary adrenal insufficiency (Addison's disease) often
develops insidiously. Although a rare disorder, it is more common in
type 1 diabetes mellitus. A 19 year old male with type 1 diabetes and
autoimmune hypothyroidism experienced recurrent severe hypoglycaemia over several months, despite a reduction in insulin dose, culminating in an adrenal crisis. Recurrent severe hypoglycaemia resolved after
identification and treatment of the adrenocortical insufficiency. In
type 1 diabetes, undiagnosed Addison's disease can influence glycaemic
control and induce severe hypoglycaemia.
Keywords: type 1 diabetes; Addison's disease; hypoglycaemia; cortisol
© 2000 by The Fellowship of Postgraduate Medicine
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