Review
Current practice
Antiplatelet use in interventional cardiology
Adrian Brodisona, Ravish Katiraa, Ranjit S Moreb, Anoop Chauhana
a Regional
Cardiothoracic Centre, Blackpool Victoria Hospital, Whinney Heys Road,
Blackpool, Lancashire FY3 8NR, UK, b St Mary's Hospital,
Portsmouth, UK
Correspondence to: Dr A Chauhan
Submitted 18 February
1999;
Accepted 13 August 1999
Thrombosis within the target vessel is one of the most feared
complications associated with coronary intervention, as it is often
associated with severe adverse clinical sequelae. This thrombosis is
mediated via the activation and aggregation of platelets and therefore
considerable effort has been directed at ways of inhibiting platelet
function. It is now mandatory to consider the use of two and often
three different antiplatelet agents, particularly when intracoronary
stents are inserted. Using these regimes, many of the adverse clinical
outcomes associated with platelet activation can be reduced.
Keywords: platelets; cardiology; antiplatelet agents; glycoprotein receptor antagonists
© 2000 by The Fellowship of Postgraduate Medicine
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