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Postgraduate Medical Journal 1999;75:737-742; doi:10.1136/pgmj.75.890.737
Copyright © 1999 The Fellowship of Postgraduate Medicine.
Postgrad Med J 1999;75:737-742 ( December )

Short report

Management of pulmonary thrombo-embolism using catheter manipulation: a report of four cases and review of the literature Peter S C Wong, Shyam P Singh, Robert D S Watson, Gregory Y H Lip

Department of Cardiology, City Hospital, Dudley Road, Birmingham B18 7QH, UK

Correspondence to: Dr GYH Lip

Accepted 7 June 1999

To date the management of pulmonary thrombo-embolism is still largely limited to anticoagulation. Heparin and oral anticoagulation have been shown to be effective in reducing recurrence and death in venous thrombo-embolism. During the acute stage, systemic thrombolytic therapy has also been advocated for the rapid dissolution of the thrombus in patients with haemodynamic instability. We describe four patients with acute pulmonary thrombo-embolism who were managed with catheter-based thrombus manipulation with intrapulmonary thrombolysis. This management strategy should be considered in patients with pulmonary thrombo-embolism who continue to deteriorate despite conventional management with anticoagulation or systemic thrombolysis.


Keywords: pulmonary thrombo-embolism; catheter manipulation; thrombus; thrombolytic therapy


© 1999 by The Fellowship of Postgraduate Medicine

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This article has been cited by other articles:

  • Kucher, N. (2007). Catheter Embolectomy for Acute Pulmonary Embolism. Chest 132: 657-663 [Abstract] [Full Text]  
  • Blann, A. D, Lip, G. Y H (2006). Venous thromboembolism. BMJ 332: 215-219 [Full Text]  

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