Short report
Fatal phenytoin hypersensitivity syndrome
U Mahadevaa, M Al-Mrayatb, K Steerb, E Leena
a Northwick Park and
St Mark's Hospitals NHS Trust, Watford Road, Harrow HA1 3UJ, UK
Department of Cellular Pathology, b Department of General
Medicine and Endocrinology
Correspondence to: Dr E Leen, Histopathology Laboratory, James Connolly Memorial Hospital, Blanchardstown, Dublin 15, Ireland
Accepted 7 June 1999
The phenytoin (hydantoin) hypersensitivity syndrome is rare but
potentially fatal. Often, as in this case, it presents with non-specific symptoms and signs, requiring a high degree of clinical suspicion for diagnosis.
Keywords: phenytoin; hydantoin; hypersensitivity.
© 1999 by The Fellowship of Postgraduate Medicine
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