Short report
Reversible cerebellar involvement in the idiopathic
hypereosinophilic syndrome
Fernando Díaz, Julio Collazos
Service of
Internal Medicine, Hospital de Galdakao, 48960 Vizcaya, Spain
Accepted 14 January
1999
We report a patient with cerebellar manifestations due to the
idiopathic hypereosinophilic syndrome, in whom magnetic resonance imaging (MRI) showed hyperintense lesions in both cerebellar
hemispheres. Following steroids and hydroxyurea administration, the
lesions on MRI disappeared, suggesting that the pathogenetic mechanism was reversible and did not cause significant structural damage. To our
knowledge, the resolution of the abnormal MRI findings have not been
reported to date in the idiopathic hypereosinophilic syndrome.
Keywords: hypereosinophilic syndrome; cerebellum; magnetic resonance imaging; hydroxyurea
© 1999 by The Fellowship of Postgraduate Medicine
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