Review
Eponyms in medicine revisited
Cogan's syndrome: an oculo-audiovestibular disease
J R García Berrocala, J A Vargasb, M Vaqueroc, S Ramón y Cajald, R A Ramírez-Camachoa
a Clínica Puerta
de Hierro, Universidad Autónoma, San Martín de Porres 4, 28035 Madrid, Spain Service of Otorhinolaryngology, b Service of Internal Medicine I, c Service
of Ophthalmology, d Service of
Pathology
Accepted 27 November
1998
Typical Cogan's syndrome is a rare disease of young adults
consisting of flares of interstitial keratitis and sudden onset of
Ménière-like attacks (nausea, vomiting, tinnitus, vertigo and hearing loss). Life-threatening aortic insufficiency develops in 10%
of reported cases. Atypical Cogan's syndrome (audiovestibular dysfunction with other types of inflammatory eye disease) is associated with vasculitis in 20% of cases and has a less favourable prognosis than typical Cogan's syndrome.
Keywords: Cogan's syndrome; hearing loss; autoimmune disease
© 1999 by The Fellowship of Postgraduate Medicine
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