Short report
Good prognosis in thyroid cancer found incidentally at surgery
for thyrotoxicosis
Louiza Vini, Stephen Hyer, Brenda Pratt, Clive Harmer
Thyroid Unit,
Royal Marsden NHS Trust, Downs Road, Sutton, Surrey SM2 5PT, UK
Correspondence to: Dr Stephen Hyer FRCP, St Helier Hospital, Wrythe Lane, Carshalton, Surrey SM5 1AA, UK
Accepted 2 September
1988
An analysis of the outcome of thyroid carcinoma incidentally
discovered in patients undergoing surgery for hyperthyroidism is
presented. Among 986 patients with differentiated thyroid cancer, 23 had presented with symptoms and signs of hyperthyroidism. Graves' disease was diagnosed in 11, multinodular goitre in eight and toxic
adenoma in four. Following thyroidectomy, histology revealed papillary
(18), follicular (four) and Hurthle cell (one) carcinoma. Tumour size
ranged from 4 mm to 5.5 cm, multifocality was detected in three
patients, and lymph node involvement in one. Two patients (one with
associated Graves' disease, one with multinodular goitre) relapsed
locally and required further surgery; one developed distant metastases
and died 7 years after initial presentation. Two patients died of
unrelated causes; the remaining 20 patients are alive and well with a
median follow-up of 16 (1-34) years. Differentiated thyroid cancer
found incidentally at surgery for hyperthyroidism has a good prognosis.
Keywords: thyroid neoplasms; thyrotoxicosis; thyroidectomy
© 1999 by The Fellowship of Postgraduate Medicine
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