Short report
Recurrent thrombo-embolic episodes: the association of
cholangiocarcinoma with antiphospholipid syndrome
S Samadian, L Estcourt
Department
of Medicine for the Elderly, St Helier NHS Trust, Wrythe Lane,
Carshalton, Surrey SM5 1AA,
UK
Accepted 8 July 1998
Antiphospholipid syndrome is a disorder of recurrent vascular
thrombosis, pregnancy loss and thrombocytopenia associated with persistently elevated levels of antiphospholipid antibodies. It was
first described in a group of patients with systemic lupus erythematosus but has since been associated with a wide range of
conditions, including other autoimmune disorders and malignancy. It can
also occur in isolation, the so-called primary antiphospholipid syndrome. We describe an elderly woman with the antiphospholipid syndrome thought to be associated with a cholangiocarcinoma.
Keywords: antiphospholipid syndrome; cholangiocarcinoma; deep vein thrombosis
© 1999 by The Fellowship of Postgraduate Medicine
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