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Postgraduate Medical Journal 1994;70:746-748; doi:10.1136/pgmj.70.828.746
© 1994 BMJ Publishing Group Ltd and The Fellowship of Postgraduate Medicine.

A small cell bronchogenic carcinoma associated with tumoral hypophosphataemia and inappropriate antidiuresis.

N. Robin, G. Gill, C. van Heyningen, W. Fraser

Departments of Medicine, Walton Hospital, Liverpool, UK.

A patient is described with small cell carcinoma of the lung, associated with profound hypophosphataemia and hyponatraemia. Increased phosphate excretion and inappropriately high urine osmolality were observed. The abnormalities are consistent with tumoral hypophosphataemia and inappropriate antidiuresis. These tumour-related metabolic abnormalities have only been described once before with this malignancy.


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