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Postgraduate Medical Journal 1988;64:899-902; doi:10.1136/pgmj.64.757.899
© 1988 BMJ Publishing Group Ltd and The Fellowship of Postgraduate Medicine.

Villous adenomas and carcinoma of the duodenum in Gardner's syndrome.

J. Sinha, R. C. Williamson

Department of Surgery, Royal Postgraduate Medical School, Hammersmith Hospital, London, UK.

Patients with Gardner's syndrome are increasingly found to have polyps on routine upper gastrointestinal endoscopy, and their risk of developing periampullary carcinoma is between 3-12%. We report a 45 year old man with Gardner's syndrome who presented with periampullary carcinoma 5 years after colectomy. Review of the literature amassed another 21 cases of periampullary carcinoma in patients with Gardner's syndrome.


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